Over-the-counter antihistamines like Claritin and Zyrtec, recommended by the Mayo Clinic, can effectively block the release of histamine and alleviate mild symptoms. Additionally, the National Center for Advancing Translational Sciences suggests systemic corticosteroids as a viable treatment, offering anti-inflammatory effects. Another option they propose is Dapsone, which reduces swelling and inhibits bacterial growth on the skin, which is particularly useful for certain skin disorders.